Pre-Seed Round Open. Investor Inquiries: esther@cloakbiotech.com
Engineered Skin Defense System

For 80 years, insect repellents have relied on chemical actives. CLOAK changes the architecture.

Every chemical repellent on the market today still relies on the same active-ingredient approach DEET introduced eight decades ago. CLOAK is the first engineered-skin microbe alternative, architected for sustained performance.

Peer Reviewed In Vivo Performance

CLOAK Maintains Efficacy. Chemical Repellents Do Not.

Chemical repellents lose effectiveness within hours of application. CLOAK's engineered microbes alter the skin's chemistry directly, sustaining protection for days to weeks rather than hours.

Sustained Mosquito Repellency Over Time

0% 20% 40% 60% 80% % REPELLENCY DAY 0 2 4 6 8 10 11 DAYS
CLOAK (Engineered-Microbes) DEET (Chemical Repellent)

Based on published, peer-reviewed mouse studies measuring repellency. Data shown until study end-point.

System Advantages

Three Failure Points, Engineered Out.

01, Chemical Signature

Zero Chemical Signature.

No active chemical agents, no residue, no detectable scent profile. Engineered biological containment removes the failure points and environmental contamination inherent to topical chemical formulations.

02, Logistics

Logistical Independence.

A single application replaces a full cycle of manual reapplication, reducing consumable resupply burden across both field deployment and civilian use.

03, Chemical Resistance

Resistance-Independent Protection.

Chemical vector control faces documented, accelerating resistance across disease-endemic regions worldwide. CLOAK modifies host-detection signaling rather than acting as a toxic active ingredient, so it is not subject to the evolutionary pressure driving that decline.

Sweat & Wash-Resistant Broad-Spectrum: Aedes, Anopheles, Culex + Sandflies Zero Resupply Dependency
55–64%
Reduction in mosquito attraction, engineered vs. wild-type microbes (Coutinho-Abreu, 2024)
11+ Days
Sustained repellency through study end-point
Regulatory & Safety Pathway

Built-In Compliance, By Design.

CLOAK addresses dual-use and biosafety considerations directly, engineered to satisfy both civilian regulators and defense procurement standards from inception.

EPA Pathway

EPA Registration Pathway

Engineered for review under existing EPA Biopesticides and Pollution Prevention Division (BPPD), responsible for all regulatory activities associated with biologically-based pesticides, with regulatory engagement initiated early.

Safety

Non-Pathogenic Engineered Strains

Base strains are naturally occurring, non-pathogenic skin bacteria engineered with a favorable safety profile.

Verified

Peer-Reviewed Efficacy Data

Efficacy data are generated using blinded study protocols and published in peer-reviewed scientific journals. Safety is supported by in vivo animal safety studies.

CLOAK Biotech

Meet the Engineering and Research Team.